What Is This?
SLU-PP-332 is a synthetic small molecule (not a peptide) that activates ERR-alpha - a nuclear receptor that acts like a master switch for mitochondrial growth, fat burning, and endurance-type metabolism in cells. Researchers use it as a pharmacological tool to study these pathways in cultured muscle cells without needing physical exercise as the trigger.
What Do Researchers Study?
Published muscle cell work shows SLU-PP-332 can activate ERR-alpha-driven mitochondrial programs, raise PGC-1alpha levels, and shift gene expression toward oxidative, endurance-associated profiles in myotube cultures. Seahorse metabolic assays confirm increased oxidative capacity after treatment.
Common Research Uses
- ERR-alpha gene program activation studies
- Mitochondrial biogenesis assays in muscle cells
- Endurance-type metabolism and fat-oxidation gene research
- Metabolic disease and insulin-resistance cell models
- Comparing ERR-alpha agonists vs PPAR and AMPK pathway tools
What the Science Is Looking At
- Turns on ERR-alpha - a master switch controlling mitochondrial growth and fat burning
- Muscle cell cultures show shifts toward endurance-type, fat-burning gene profiles
- Useful pharmacological tool for studying exercise biology mechanisms in vitro
- Raises mitochondrial density markers (PGC-1alpha, TFAM) in cultured myotubes
- Helps researchers dissect mitochondrial biogenesis pathways independent of exercise stimulus
How It Works — In Plain Terms
Mimics Exercise in a Pill
Called an 'exercise mimetic' — studied for triggering the same metabolic pathways your body activates during a workout, without actual exercise.
Burns Fat Through Mitochondria
Works on ERR receptors in mitochondria — the energy factories in your cells — boosting fat oxidation and endurance markers in research.
Boosts Stamina Pathways
Animal studies show improved running endurance and metabolic flexibility — why it's gaining attention in longevity and fitness research.
Metabolic Switch
Helps cells shift from storing fat to burning it — a core mechanism researchers study in obesity and metabolic disease models.
Product Specifications
| Compound | SLU-PP-332 (ERR-alpha agonist) |
|---|---|
| Quantity | 5 mg per vial |
| Form | Lyophilized powder |
| Purity | 99%+ (HPLC) |
| Storage | -20 C, desiccated |
Order SLU-PP-332
99%+ Purity • Third-Party Tested • COA Included • Ships Canada 1-2 Days
Multi-vial deal: 2+ vials of this peptide = $10 off per vial!