What Is This?
Semax is a small peptide based on a piece of ACTH (a natural hormone), modified to be more stable in solution and culture. It is heavily studied for increasing BDNF and other growth factors that help neurons survive and form new connections - especially when brain cells face oxidative stress, low oxygen, or excitotoxic challenge in vitro.
What Do Researchers Study?
Researchers use Semax to measure brain growth factor levels (BDNF, NGF, GDNF), test neuron survival in low-oxygen culture conditions, and study how well neurons form new connections and dendritic branches. Hippocampal and cortical neuron cultures are the most common models.
Common Research Uses
- BDNF and neurotrophin level measurements in neuronal cultures
- Low-oxygen and oxidative stress protection tests in brain cells
- Synaptic connection, spine density, and branching studies
- Excitotoxicity and glutamate-challenge protection assays
- Comparative studies alongside Selank in CNS peptide research
What the Science Is Looking At
- Linked to higher BDNF, NGF, and GDNF levels in neuronal cultures - key factors for neuron health
- Helps brain cells survive low-oxygen and oxidative challenge in culture
- Supports markers of new synaptic connections in hippocampal cells
- Shows protective effects against excitotoxicity and free-radical damage in neuron studies
- Well-documented in Russian and international CNS peptide literature as a reference compound
How It Works • In Plain Terms
Brain Fertilizer
Increases BDNF • often called 'brain fertilizer' • a protein that helps neurons grow, connect, and survive. More BDNF means healthier, more resilient brain cells.
Sharper Focus and Memory
Studied for improving attention, learning, and memory in cognitive research • derived from a natural stress hormone fragment with brain-boosting modifications.
Protects Neurons From Damage
Shows protective effects when brain cells are stressed by low oxygen, toxins, or inflammation • helping them survive what would normally kill them.
Calm Energy, Not Jittery
Unlike stimulants, Semax is studied for clear-headed focus without anxiety or crash • a smoother cognitive boost in neuronal culture models.
Product Specifications
| Sequence | ACTH(4-10) analog with stability modifications |
|---|---|
| Sizes | 5 mg and 11 mg vials |
| Form | Lyophilized powder |
| Purity | 99%+ (HPLC) |
| Storage | -20 C |
Order Semax
99%+ Purity • Third-Party Tested • COA Included • Ships Canada 1-2 Days
Multi-vial deal: 2+ vials of this peptide = $10 off per vial!