What Is This?
Pinealon (Glu-Asp-Arg) is a synthetic three-amino-acid peptide developed in Russia, modeled on short peptides associated with the pineal gland - the brain region that helps regulate circadian rhythm and melatonin production. It belongs to the Khavinson family of "bioregulator" peptides studied for how they influence gene activity directly in brain, retinal, and pineal cell cultures.
What Do Researchers Study?
Research looks at Pinealon for protecting retinal ganglion cells from oxidative and excitotoxic damage, studying melatonin synthesis enzymes and clock genes in pinealocyte cultures, and helping cortical neurons survive low-oxygen conditions. Gene expression microarrays are often used to see which pathways shift after treatment.
Common Research Uses
- Retinal ganglion cell protection and viability assays
- Pineal gland and melatonin pathway research in cultured cells
- Neuron survival under low-oxygen and oxidative challenge
- Short-peptide bioregulator gene expression studies
- Circadian rhythm and clock-gene pathway research
What the Science Is Looking At
- Studied for protecting retinal nerve cells from oxidative stress in culture
- Examined for effects on melatonin synthesis enzymes and sleep-cycle related genes
- Shown in cell studies to support neuron survival under low-oxygen conditions
- Part of a well-known class of short peptides thought to influence gene activity directly
- Often grouped with Epithalon and other Khavinson peptides in aging-cell research programs
How It Works - In Plain English
Retinal Protection
Cell culture work describes preserved retinal ganglion cell viability under oxidative and excitotoxic challenge. Researchers use this model to study neuroprotection pathways in the eye.
Sleep-Cycle Biology
Studied for effects on melatonin synthesis enzymes (e.g. AANAT) and pineal gland cell function markers in pinealocyte cultures.
Gene Normalization
Investigated for shifting age-related gene expression patterns in cultured brain cells toward profiles seen in younger cell models.
Short Peptide Advantage
At just three amino acids, Pinealon is small enough to enter cells easily - a design feature researchers highlight when studying direct gene effects in vitro.
Product Specifications
| Compound | Pinealon (Glu-Asp-Arg tripeptide) |
|---|---|
| Quantity | 10 mg per vial |
| Form | Lyophilized powder |
| Purity | 99%+ (HPLC) |
| Storage | -20 C |
Order Pinealon
99%+ Purity • Third-Party Tested • COA Included • Ships Canada 1-2 Days
Multi-vial deal: 2+ vials of this peptide = $10 off per vial!