Tesamorelin
Stabilised GHRH analog with extensive investigational pharmacology data.
What Researchers Study
Tesamorelin (TH9507) is a synthetic GHRH analog with a trans-3-hexenoic acid modification for enzymatic stability. It is the most clinically documented GHRH analog, with published trials examining GH pulsatility, visceral adipose markers, and cognitive endpoints.
Primary Research Applications
- GHRH receptor pharmacology reference
- Visceral adipose cell and cohort research
- Hepatic lipogenesis enzyme studies
- Somatotropic axis activation assays
Benefits Researchers Are Exploring (in simple terms)
Mechanisms Under Investigation
GHRH Potency
Potent, sustained GHRH receptor activation with well-characterised PK/PD.
Hepatic Lipid
Effects on triglyceride synthesis and VLDL secretion in hepatocyte cultures.
Adipose Metabolism
Measurable adipose tissue marker changes in controlled investigational cohorts.
Reconstitution Reference (how to mix it for lab use)
| Common vial size | 10 mg |
| Reconstitution | 2 mL BAC water = 5 mg/mL |
| Storage | -20 C |
| Investigational reference | Extensive published PK data available |
Dosing Schedule Options from Research
Example Options Used in Studies
- Investigational literature: daily administration over 12-26 weeks in defined cohorts
- Visceral adipose endpoints often measured at 12 and 26 week timepoints
- Pituitary cell research: single bolus and chronic exposure protocols
- Hepatocyte lipogenesis assays: 24-72 hour exposure windows
100-Unit Insulin Syringe Conversion Chart
Reconstitution used for these calculations: Calculate concentration (mg/mL) from the reconstitution table above. U-100 insulin syringes: 100 units = 1 mL total volume.
Important: We have already done all the math for you. U-100 insulin syringes are marked in "units" (100 units = 1 mL). Just draw the exact number of units listed below for each dose. No calculations required on your end.
| Dose (mg) | Units on 100-unit syringe (pre-calculated) |
|---|---|
| Use: Units = (desired mg / mg per mL concentration) × 100. See primary literature for exact values. | |
These unit amounts assume the exact concentration listed above. Always double-check your own reconstitution volume against the chart.
Safe Research Cycle Guidelines
Example Cycle References from Research Literature
- Consult published research literature and your institution's approved protocols for recommended cycle lengths, titration, and recovery periods specific to this compound.
Research Notes
Tesamorelin serves as a well-characterised GHRH reference compound with extensive published pharmacology.
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