CJC-1295 (No DAC) / Ipamorelin
GHRH + GHRP research stack for pituitary somatotropic signalling.
What Researchers Study
This blend pairs CJC-1295 (without DAC), a GHRH analog, with Ipamorelin, a selective ghrelin receptor agonist. Together they represent the standard GHRH+GHRP research combination for studying pulsatile growth hormone release in somatotroph models.
Primary Research Applications
- Pulsatile GH release perfusion studies
- IGF-1 axis hepatocyte co-cultures
- Somatotroph selectivity assays
- Downstream adipocyte and myocyte metabolic studies
Benefits Researchers Are Exploring (in simple terms)
Mechanisms Under Investigation
GHRH Stimulation
CJC-1295 (no DAC) activates GHRH receptors with short half-life suitable for pulsatile research.
Selective GHRP
Ipamorelin stimulates GHS-R1a with minimal cortisol/prolactin impact versus older GHRPs.
Synergy
Combined application produces amplified GH secretion versus either peptide alone in somatotroph assays.
Reconstitution Reference (how to mix it for lab use)
| Common vial size | 10 mg total (5 mg each) |
| Reconstitution | 2-3 mL BAC water |
| Storage | -20 C |
| Timing research | Literature examines pre-bed and fasted-state timing for pulsatile GH patterns |
Dosing Schedule Options from Research
Example Options Used in Studies
- Research models: Draw **4-12 units** (100-300 mcg CJC + 100-300 mcg Ipa) on 100-unit syringe 5 days on / 2 off or daily for 8-12 weeks. Use 10 mg total blend + 2-3 mL BAC = ~3-5 mg/mL concentration.
- Pre-sleep administration timing studied for nocturnal GH pulse amplification.
- Somatotroph perfusion: coordinated GHRH+GHRP bolus protocols.
- Often combined with elevated IGF-1 monitoring endpoints over 8-16 week windows.
100-Unit Insulin Syringe Conversion Chart
Reconstitution used for these calculations: 10 mg total (5 mg each) + 2-3 mL bacteriostatic water = ~3-5 mg/mL concentration for the blend (standard for CJC/Ipamorelin).
Important: We have already done all the math for you. U-100 insulin syringes are marked in "units" (100 units = 1 mL). Just draw the exact number of units listed below for each dose. No calculations required on your end.
| Dose (mg) | Units on 100-unit syringe (pre-calculated) |
|---|---|
| 100 mcg each daily | ~4-6 units total per day at 5 mg/mL |
| 200-300 mcg each daily | ~8-12 units total per day |
These unit amounts assume the exact concentration listed above. Always double-check your own reconstitution volume against the chart.
Safe Research Cycle Guidelines
Example Cycle References from Research Literature
- Typical research cycle: 8-12 weeks on at 100-300 mcg each, 5 days on/2 off or daily, minimum 4 weeks off.
- Pre-sleep timing for pulse studies.
- Key: Approved protocols.
Research Notes
The no-DAC CJC form is preferred for pulsatile research; DAC form provides extended GHRH elevation unsuitable for pulse studies.
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